The RTN4 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to NI220/250, NOGO A, NOGO C, NOGO-B, NSP-CL, Reticulon 4, RTN-X, and Rtn4. This antibody recognizes Human, Mouse, and Rat antigen. The RTN4 Polyclonal Antibody has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified